Journal: The Lancet. Global Health
Article Title: Safety and efficacy of oral fexinidazole in children with gambiense human African trypanosomiasis: a multicentre, single-arm, open-label, phase 2–3 trial
doi: 10.1016/S2214-109X(22)00338-2
Figure Lengend Snippet: Study flowchart of complete 18-month data g-HAT=gambiense human African trypanosomiasis. QTcF=Fridericia's corrected QT-interval. *Three patients had an abnormal ECG and one patient was pregnant.
Article Snippet: We thank Didier Kalemwa and Patrice Kabangu for their help in site selection and training; Frederic Mistretta, Didier Not, Adrien Beauvais, and Michèle Ribaud for data management and statistical analysis; Pere Simarro for his invaluable advice; Pascal Voiriot, Catherine Da Silva, and Yasmin Khan of Cardiabase (Banook group) for their support in ECG handling and analysis; Mathieu Felices for support in ECG analysis and interpretation and Sarah Lezzar for support in pharmacokinetic analysis and interpretation, both of PhinC Development; Valerie Wauthier of SGS (Société Générale de Surveillance) for her participation in dry blood spot sampling analysis; Gaële Ducher (Scinopsis) and Vanessa Gray-Schopfer (OmniScience SA) for providing medical writing services funded by DND i; and special thanks to Louise Burrows (DND i ) for carefully editing the final manuscript.
Techniques: